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Pituitary growth hormone secretion in the turbot, a phylogenetically recent teleost, is regulated by a speciesspecific pattern of neuropeptides

& Holehouse, A

Stimulation of the receptors upon binding of its ligands, for example with interalia AGE, leads to the activation of several molecular signalling pathways, including the PI3K/AKT, JAK/STAT, NF-B, Ras/MAPK, Rac1/cdc42, p44/p42, p38 and SAP/JNK/MAPK pathways, which contribute to the expression of transcription factors, such as NF-B, STAT3, HIF-1, AP-1 and CREB

However, we did not study circadian-related markers such as CLOCK, BMAL1, CRY, and PER1/2

74 As spatial transcriptomics and multi-modal data become central to understanding aging tissues, new AI frameworks are emerging to integrate these layers

The optimal temperature for growth ranges from 25 to 35C, although the tree can survive temperatures as high as 48C for short periods (Palada et al