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According to the literature, the autosomal recessive inheritance pattern is generally associated with a more severe clinical phenotype compared to autosomal dominant cases [38]

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Vet Immunol Immunopathol 139:308312 Conejeros I, Jara E, Carretta MD, Alarcn P, Hidalgo MA, Burgos RA (2012) 2-Aminoethoxydiphenyl borate (2-APB) reduces respiratory burst, MMP-9 release and CD11b expression, and increases l-selectin shedding in bovine neutrophils

Cellular injury induced by oxidative stress is mediated through lysosomal damage

Importance of natural antioxidants for health The importance of natural antioxidants has been increasingly investigated for oxidative-antioxidative balance and wellness because of the consumer concern regarding the safety of using synthetic antioxidant and its low cost and strong H donating capacities

Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells