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Behaving as the terminal electron acceptor during cellular respiration, the high rate of O 2 electron flux is accompanied by an increased risk of ROS formation, which can induce irreversible damage to cellular organelles and their processes (Case 2017)

10.1002/ange.201500478 93 LiuY.ZhaoY.ChenX

Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC

The bodys natural glutathione levels may decrease over time because of age, environmental exposure, and other factors

Nevertheless, out of an abundance of caution, Life Extension recommends that people who have or have had lung cancer consult their physician before supplementing with vitamin E or NAC, especially at high doses