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Loss of PCBP expression leads to prolonged HIF1 half-life without altering steady-state levels of HIF1 transcripts

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Whilst advances in targeting ROS and oxidative stress have led to the development of novel pre-clinical therapeutic methods, due to the complex nature of ROS in wound healing, gaps in knowledge remain concerning the specific cellular and molecular functions of ROS in wound healing

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Naunyn Schmiedebergs Arch Pharmacol, pp 126 Przybylska S, Tokarczyk G (2022) Lycopene in the prevention of cardiovascular diseases

Studies also evaluated the synergistic effect of PERK inhibitors with anti-PD-L1 in the B16F10 tumor model, showing promising outcomes