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267 Seal et al

Int J Gen Med (2021) 14:1011729

Hametner, S

Activated AKT enters the nucleus, activates or inhibits many downstream pathways, and regulates cell proliferation, apoptosis and metabolic processes 50

A subproduct of these methylation reactions is S-adenosylhomocysteine, which is hydrolysed to adenosine and Hcy ( Reference Selhub 15 )

Two patients (17.0%) with stage IV disease underwent chemotherapy with rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisolone