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High-dose nVNS significantly reduced brain lesion volume, improved neurobehavioral performance, and reduced cortical volume loss compared to the control and low-dose groups

Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4 + T cell subset in systemic lupus erythematosus

Mixed Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant use of opioids with other opioid analgesics, such as butorphanol, nalbuphine, pentazocine, may reduce the analgesic effect of acetaminophen and codeine phosphate tablets and/or precipitate withdrawal symptoms

563 Critically, implementing personalized mitochondrial-targeted therapies requires transcending traditional single-target paradigms, establishing a multidimensional evaluation framework encompassing genomic stability, metabolic plasticity, and microenvironment adaptability

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