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This narrative review comprehensively synthesizes current scientific knowledge regarding the role of mitochondrial dysfunction in major CVDs, such as hypertension, coronary artery disease, and heart failure, as well as neurodegenerative and vascular cognitive disorders, including AD and VCI

Issue 1: a thin clinical-trial evidence base relative to the marketing The public GHK-Cu literature spans more than 250 papers, the majority of which are in-vitro (cell-culture) or small animal model work

(Regentherapy) Hence, removing senescent cells is a promising strategy for health-span extension (improving the period of life spent in good health) and possibly delayed onset of age-related diseases

Keywords liposomes, growth factors, delivery, tissue, regeneration, defects, neurodegeneration, liver, disease, targeting, gene therapy LIPs as carriers of active substances Liposomes (LIPs) are defined as round vesicular structures constructed mainly by phospholipids and cholesterol (Chol) (Fig

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