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Uno et al 253 have contributed insights into the protective effects of CYP1A1 against NAFLD based on findings that a Western diet plus benzo[a]pyrene triggered significant hepatic steatosis, inflammation, and fibrosis in CYP1A1-knockout mice but not in wild-type animals by interrupting the homeostasis of bile acid and lipid metabolism

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This approach offers arrhythmic protection during the vulnerable inflammatory phase (59)

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