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nonetheless, heterogeneous study designs impede comparability of trials [39]

GHK-Cu upregulates collagen synthesis and modulates matrix metalloproteinase (MMP) activity, influencing both new collagen deposition and turnover of disorganized tissue

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As previously mentioned, the biomaterial used for islet transplantation could also induce host response and cause the formation of fibrous capsules, thus impairing the transport functions of the selective permeable encapsulating membrane