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accepted 10 February 2010)ISSN 0954-6634 print/ISSN 1471-1753 online 2010 Informa UK Ltd.DOI: 10.3109/09546631003801619

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Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation