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The American Heart Association therefore recommends the consumption of food rich in antioxidant vitamins and other nutrients, but does not recommend the use of vitamin E supplements to prevent cardiovascular disease

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Unreconstituted vials are most stable when stored in a refrigerator

Nowadays, the discovery of CFTR modulators that aim to increase or potentially restore the function of the disease-causing CFTR protein (Lopes-Pacheco, 2016) as well as the development of gene therapy have provided new opportunities to treat CF (Perry et al., 2017)

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Furthermore, itaconate inhibits M2 macrophages polarization by inhibiting JAK1 and STAT6 phosphorylation (138)