napqi glutathione mechanism File:Acetaminophen metabolism.jpg Solved The following figure shows
Solved The following figure shows the metabolism of the A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Pharmacokinetic profile of metabolites by heart cutting two dimensional liquid chromatography: A focus on paracetamol analysis ScienceDirect Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram The molecular mechanisms of acetaminophen induced hepatotoxicity and its potential therapeutic targets PMC Fasting depletes Glutathione, turning "safe" Paracetamol doses into a liver toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. #MedEd #
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