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NICE Clinical Knowledge Summaries and British Society for Haematology guidelines support B12 supplementation in these clinical contexts, with treatment regimens tailored to the underlying cause

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doi: 10.1016/j.fertnstert.2011.03.030 79 WangJShenXXHuangXHZhaoZM

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It slows down the breakdown of collagen and elastin, essential proteins for skin structure and elasticity, thereby preventing premature aging

However, single-agent therapy, which has had a positive impact on cell lines and preclinical models, has not been approved for aggressive TNBC