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Dosing of rifampin higher than 150 milligrams PO BID caused significant Herxheimer reactions however, suggestive of an active intracellular infection, and any attempt to lower the Bicillin injections to 1.2 million units twice a week resulted in an increase in headaches and mood swings

10.1016/j.survophthal.2019.01.011 13 CudeiroJ.RivadullaC., and (1999)

This metabolic shift in KO cells coincides with reduced PPP reliance and elevated glucose uptake, potentially facilitated by a more alkaline cytosolic pH

it is abundant in citrus fruits, berries, and peppers

doi: 10.1016/j.tibtech.2023.10.001 189 ManciniAGentileMTPentimalliFCortellinoSGriecoMGiordanoA

Some more people called William, in this case William Osler, a Canadian, and his colleague William Gardner, also contributed to the publication of papers about Pernicious Anaemia, in particular relating to observations on gastric atrophy, neuropathy and red cell changes in the blood and bone marrow