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We found robust neurodegenerative features in cognitively impaired aged degus, including hippocampal neuronal loss, altered parvalbumin and perineuronal net staining in the cortex, and increased c-Fos neuronal activation in the cortex that is consistent with the neural circuit hyperactivity that are commonly reported in human Alzheimers Disease patients, explained corresponding author Xiangmin Xu, PhD, professor and Chancellors Fellow of anatomy and neurobiology in the UCI School of Medicine, and director of the Center for Neural Circuit Mapping

She is a member of the Advisory Council for Communities Foundation of Texas

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2019;63(8)10.1128/aac.00199-00119

Interactions between obesity and obstructive sleep apnea: implications for treatment

Sullivan, Kelly L.|Staffetti, Joseph F.|Hauser, Robert A.|Dunne, Peter B.|Zesiewicz, Theresa A