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A total of 1.4 billion people are anticipated to be eligible for vaccination (Peacocke et al., 2021), many of whom are in the highest risk groups for death and serious illness

Because SDH is the only enzyme that participates in both the TCA cycle and the ETC, we speculated that the ETC might be compromised in Gclc -deficient FoB, thus explaining the inhibition of SDH and the accumulation of succinate