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doi: 10.1158/0008-5472.CAN-06-3137 137 LeBleuVSOConnellJTGonzalez HerreraKNWikmanHPantelKHaigisMCet al

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Additionally, AMDs pathogenesis involves the loss of RPE-derived VEGF signaling and defenestration of usually high permeable choriocapillaries in atrophied RPE areas, which disrupts retinal permeability [440, 441]

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