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First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid

Nrf2, in turn, regulates the expression of GPx8 and affects calcium regulation in the endoplasmic reticulum through calcium ATPase (Granatiero et al

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The column was Waters XBridge C8 column and gradient was from 20-90% MeCN/0.1% formic acid over 12 min

Abstract Glutathione peroxidase 4 (GPX4), as the only enzyme in mammals capable of reducing esterified phospholipid hydroperoxides within a cellular context, protects cells from ferroptosis