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Comput Struct Biotechnol J

The treatment of lactone 71 with thiourea in a strong mineral acid via alkaline hydrolysis of the isothiuronium salt easily yielded DHLA, which afforded the desired ALA after oxidation

Binder DC, Ladomersky E, Lenzen A, Zhai L, Lauing KL, Otto-Meyer SD, et al

Mann et al., 2016[84])

On this basis, we further investigated the impact of c-Myc suppression on GGCT expression, and the results showed a significant reduction in GGCT protein levels (Fig