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Description

In vitro cytotoxicity assays using SH-SY5Y (human neuroblastoma), Caco-2 (intestinal permeability), and hCMEC/D3 (human brain endothelial) cells demonstrated that nanoencapsulation significantly reduced the inherent cytotoxicity of free coumarin

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Genetic variations in these key enzymes may collectively contribute to elevated estrogen levels in uterine fibroid tissue by enhancing E 2 synthesis and altering the balance of E 2 metabolic pathways [28,29]