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Microenvironment and tumors-a nurturing relationship

234 DSF/Cu treatment also profoundly impairs mitochondrial homeostasis, increasing the free iron pool and exacerbating lipid peroxidation, ultimately culminating in ferroptosis triggered by p62 phosphorylation-mediated NRF2 accumulation

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(2024), Zhang Q

NP versions of VCO or GSH, or their combination, significantly reduced tissue TNF- and IL-1 levels in rats compared to those treated with conventional drugs (Fig

The residue is replaced by aspartate in poorly active ScGrx8, by histidine in protein disulfide isomerases and by proline in thioredoxins 11,12,33