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[6] Caution is advised in patients with advanced renal impairment or those receiving dialysis, given the renal clearance of carnitine and the risk of accumulation

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The sweet spot is age-adjusted high-normal , supporting muscle and bone while avoiding overstimulation

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These include gastrointestinal disorders, such as Crohns disease or celiac disease, and surgeries like gastric bypass that alter the digestive tract

Appetite changes are less consistently reported with AOD-9604 than with semaglutide and in controlled studies, most short-term safety signals mirrored placebo rates