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Description

Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum

Biophys J (1989) 56(6):105369

During ferroptosis, Treg cells exhibit elevated mitochondrial superoxide (mitoSOX), disrupting OXPHOS and Fatty Acid Oxidation (FAO) - critical metabolic pathways that maintain Treg cells survival and suppressive function ( + T cells, potentiating anti-tumor immune responses