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The LEADER trial 28 (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) studied a 1.8-mg dose in more than 9,000 patients with type 2 diabetes and found the incidence of acute pancreatitis was similar between the liraglutide and placebo groups (0.4% vs 0.5%, respectively)

C The percent ionized is the ratio of the concentration of PhCO 2 to the analytical concentration, multiplied by 100: Because only 3.6% of the benzoic acid molecules are ionized in a 0.0500 M solution, our simplifying assumptions are confirmed