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Dosing above 120mg/day shows no additional enzyme inhibition benefit but significantly increases peptide consumption cost

Plumbagin increased NAD(P)H quinone dehydrogenase 1 (NQO1) activity and decreased xCT expression, resulting in NQO1-dependent glioma cell death

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245 In human astrocytes neurotropic flaviviruses increase autophagy, although viral replication is autophagy-independent

Glutathione influences immune-cell function, redox-sensitive signaling, and responses to infection

This conservative approach identifies any unusual sensitivity before significant exposure occurs