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doi: 10.1021/jf902171h 243

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These changes suggest a disruption in several metabolic pathways, including the biosynthesis of phosphatidylethanolamine, fatty acid synthesis, pyruvate metabolism, and mitochondrial acetyl group transfer, as indicated by pathway enrichment analysis

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The anti-CD38 phycoerythrin (PE) and anti-CD138 fluorescein isothiocyanate (FITC) antibodies, and APO-DIRECT kit (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)) were purchased from BD Biosciences (San Jose, CA, USA)

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The dosages that researchers used in these studies ranged from 336 mg daily of cinnamon extract to 1500 mg daily in capsule form over 6 to 24 weeks, indicating the need for further investigations to determine the right dosing and duration of therapy

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