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Also, the variable bioavailability of cannabinoids requires the development of quality-controlled extracts, with a pharmacological profile that allows the administration of correct doses for optimal therapeutic effects

& Ammar-Keskes, L

doi: 10.1126/science.1209985 109

In addition to being a biomarker, xCT has been proposed as a therapeutic target for drug-resistant cancer types, such as triple-negative breast cancer, pancreatic cancer, and hepatocarcinoma, that depend on xCT for survival (78, 220, 225, 226)