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They can also help maintain healthy weight and prevent long-term complications

Since this enzyme provides detoxification of the final product of lipid oxidation, 4-hydroxynonenal (4-HNE), deletion of the corresponding gene was expected to contribute to oxidative damage accumulation and life shortening

Disclosure of interest: Jiajie Xu: nothing to disclose

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Others have suggested that the presence of the MPO protein, but not necessarily its activity, is required to promote NETosis [140, 348], however, the aforementioned studies showing effects of MPO inhibitors seem to suggest that the mere presence of the enzyme itself is not sufficient

doi: 10.3168/jds.2019-18047 13 GraebinN.SchfferJ.DiandraA.PlinhoH.MarcoA.RafaelR