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Equally important is the integration of these devices into clinical workflows

The ATP binding cassette subfamily A member 1 (ABCA1) is a major regulator of cellular cholesterol efflux, while the low-density lipoprotein receptor (LDLR) controls cholesterol uptake

Medical therapy comprises oral treatment with Potaba, colchicine, tamoxifen, vitamin E, phosphodiesterase-5 inhibitors, antioxidant substances, penile injections with anti-fibrotic and anti-inflammatory substances, antioxidants (pentoxifylline, verapamil, corticosteroids, collagenase, interferon, etc.), as well as physical treatments (extracorporeal shock wave therapy, iontophoresis, vacuum, and penile traction devices) [15,16,17]

The NOEL was 255 mg/m 3 , 6-h TWA (LOEL = 1050 mg/m 3 , 6-h time weighted average) (Appelman et al., 1986)

The end result is a shift in energy balance in favour of fat breakdown

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