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9 , e1003774 (2013)

also found a significant relationship between MS and B 12 deficiency.[13] Another study reported that serum B 12 concentration in MS patients is related to the age of onset of the disease.[16] According to that report, B 12 concentration was significantly lower in those who experienced the onset of first neurological symptoms prior to age 18 years compared to patients in whom the disease first manifested after age 18

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Hence, large numbers of mature macrophages infiltrated the muscle fiber-deficient foci and increased the production of ROS in the mdx mice

doi:10.1093/ajcn/76.6.1249 Stiksrud B, Nowak P, Nwosu FC, et al