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In a randomized, double-blind, placebo-controlled study, women with PCOS were given 200 mg of ellagic acid daily for eight weeks ( Standard pharmacological treatments such as oral contraceptive pills (OCPs), metformin, clomiphene citrate, and letrozole remain first-line options for PCOS ( Table 4 ) underscores the distinctions between apigenin, ellagic acid, and standard therapies in terms of molecular targets, therapeutic effects, evidence base, and side-effect profiles

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