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Every bioavailability and half-life number above comes from rodent and cell-culture work

2 Metagenomic analysis of fecal bacteria during in vivo reprogramming

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(2011) Antimalarial drug sensitivity profile of western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay and molecular analysis

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When calculating the rebate owed by manufacturers for a rebatable drug that has more than one manufacturer, we proposed to codify the policy from section 50.13 of the revised Medicare Part B Drug Inflation Rebate Guidance to multiply the total rebate amount calculated for the billing and payment code by the following quotient: (Sum of the individual manufacturer's billing units sold during the applicable calendar quarter for all NDCs of the manufacturer assigned to the billing and payment code, as reported in the ASP data submissions) divided by (Sum of all manufacturers' total billing units sold during the applicable calendar quarter for all NDCs of the Part B rebatable drug assigned to the billing and payment code, as reported in the ASP data submissions) We received public comments on this calculation approach