interaction of chloroacetamide electrophiles with cellular glutathion Covalent inhibitors bacterial peptidoglycan biosynthesis enzyme MurA warhead Dual inhibition of carbonic anhydrase
Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis induced tumor cell death ScienceDirect Electrophilic compound screening identifies GPX4 dependent ferroptosis as a senescence vulnerability Nature Cell Biology Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development PMC The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Formation of protein derived electrophiles in ribonuclease A by biologically relevant oxidants ScienceDirect Overexpression of Glutathione S Transferases in Human Diseases: Drug Targets and Therapeutic Implications
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