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These molecules activate and recruit immune cells (M1 macrophages, neutrophils, Th17 cells), which in turn exacerbate oxidative stress and iron dysregulation, creating a self-amplifying cycle

[DOI] [PubMed] [Google Scholar] 70.Batumalaie K., Zaman Safi S., Mohd Yusof K., Shah Ismail I., Devi Sekaran S., Qvist R

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PMID: 38653359 Am J Pathol Dehydroepiandrosterone Prevents Collagen Loss by Regulating HIF-1 Expression and Mitophagy in Hypoxic Human Scleral Fibroblasts