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Multiple factors, such as genetic background, environmental and intraluminal factors, and mucosal immune dysregulation, have been implicated in the pathogenesis of UC 2,3

Preexisting disease The preexisting liver disease significantly impacts susceptibility to DILI in several ways

Although both public plans and commercial policies regarding approval for HCV treatment are constantly changing, these payers typically cover DAA therapies when any extrahepatic manifestation exists, despite level of hepatic fibrosis

Virological response (VR, HBVDNA 3 months break of insurance coverage within the 12 months before first liver complication, who received a non-liver transplant within 5 years of their first liver complication, or with CHB diagnosis after insurance coverage ended were excluded

.And all participating teams whose names cannot be mentioned one by one.