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As Th17 cells appear to contribute to nigrostriatal degeneration (206, 207), the beneficial effect of T reg may be due to their ability to inhibit TH17 cells

PLoS Med 17, e1003084 (2020)

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Occupational metal exposures and the risk of Parkinsons disease

In this review, we describe common methods associated with gene methylation, including bisulfite sequencing PCR (BSP), pyrosequencing technology (PYR), methylation-specific polymerase chain reaction (MS-PCR/MSP), methylation-sensitive high-resolution melting (MS-HRM), methylation sensitive single nucleotide primer extension (MS-SnuPE), Epityper, Droplet digital PCR (ddPCR), methylation-sensitive restriction enzyme (MSRE) analysis, COBRA and PacBio SMRT sequencing