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G.BartensC.FischerM.FridrichP.SteltzerH.DrumlW

Importantly, Set7/9-dependent methylation of -catenin is enhanced under oxidative stress conditions, thus forming a regulatory mechanism for the WNT/-catenin signaling during the oxidative stress response [132]

GPX4, originally known as PHGPX (phospholipid hydroperoxide glutathione peroxidase), was initially purified in porcine liver or heart in 1982 as a peroxidation-inhibiting protein on liposomes and biological membranes in the presence of glutathione (GSH) [10]