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Description

Blank and Goodman 2009

When something triggers the brains immune system, this inflammation can move like a slow burning fire moving through the brain, and slowly damaging brain tissue along the way and causing poor brain function

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The authors hypothesized that resveratrol could mitigate these alterations by regulating Thoc5, a factor involved in RNA transport and processing

Mechanistically, the authors found that STAT1 vitcylation inhibited the interaction with the phosphatase TCPTP, thereby preventing the dephosphorylation of STAT1