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Therefore, to reduce the ROS activity, host cells are evolved with three types of SODs such as NiSOD, Fe or MnSOD, and CuZnSOD to control the ROS activity produced by itself

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Figure 6 Trichothecenes are small molecular inhibitors of protein synthesis and trigger ribotoxic stress by binding to the peptidyl transferase site of the large 60S subunit of eukaryotic ribosomes (Garreau De Loubresse et al., 2014)