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Anemia in chronic kidney disease is independently associated with risk of death

Constipation is the most frequent autonomic feature affecting PD individuals and is determined by both neurogenic and non-neurogenic factors, such as reduced mobility and abdominal muscle tone, a diet poor in fibers and insufficient fluid intake, all contributing to a prolonged gastrointestinal transit time and sometimes megacolon [251]

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While organic vegetables sometimes contain small amounts of B12 from the soil, it is usually washed off during food preparation

A lack of B12 can cause nerve damage, leading to pain and numbness