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Consequently, and in the words of Pollack, biological catalysis may resemble generic catalysis, involving little more than high concentrations of EZ-generated protons . Therefore, given that according to Equations 6-9 and 1 the network hypothesis does not appear to violate known chemistry and biochemistry, the notion that catalase activity during H 2 O 2 disproportionation might also be occurring in the cytoplasmic aqueous milieu, does not seem too far-fetched

As a key antioxidant transcription factor, NRF2 activity decreases during heart failure, while miRNAs modulate NRF2 and its associated antioxidant proteins through EV, thereby regulating oxidative stress [166]

CNS Drugs 29 (1), 4753

Decreased glutathione found in macrophage cells from children with chronic asthma has been shown to be related to decreased bacterial phagocytosis [96]

*Correspondence: Ana Maria Castejon [email protected] This article was submitted to Child and Adolescent Psychiatry, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.3390/foods12010096, [DOI] [PMC free article] [PubMed] [Google Scholar] 176.Lane KE, Li W, Smith C, Derbyshire E