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Vitamin B9 (folate/folic acid) - Vitamin B9 is involved in the metabolism of homocysteine, an amino acid that has been linked to an increased risk of cardiovascular disease

Jackson et al., 2006)

[14] [15] It's important to note that folic acid must not be used to treat anaemia without first excluding B12 deficiency, as it can mask the haematological signs while allowing neurological damage to progress

one or more chemical entities e.g., nicotinamide riboside, nicotinamide mononucleotide the invention encompasses a method of providing muscular therapy by contacting a cell expressing NNMT with a NNMT inhibitor (such as a cation of Formula I or IA, or otherwise disclosed herein) and one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that modulates intracellular NAD+ levels to provide muscular therapy

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