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2025 doi: 10.1002/bit.70033

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Shearn, Sharon Baumel-Alterzon Frontiers in Endocrinology.2025;[Epub] CrossRef GLP-1 Analogue-Loaded Glucose-Responsive Nanoparticles as Allies of Stem Cell Therapies for the Treatment of Type I Diabetes Joana Moreira Marques, Rute Nunes, Ana Margarida Carvalho, Helena Florindo, Domingos Ferreira, Bruno Sarmento ACS Pharmacology & Translational Science.2024

Previous studies suggested that such nanoparticles can be involved in cytotoxicity, oxidative stress, and genotoxic alterations within biological systems (314)

Increasing concentrations of HQ in the presence of L-tyrosine, resulted in an increase in the K m value while the V max remained constant, an indication of a competitive inhibition mode on the monophenolase activity, with a K I of 40 M and apparent K m and V max values of 0.07 mM and 9.0 mole min 1 mg 1 , respectively (Fig

Table 3: Laboratory Abnormalities Worsened from Baseline in 20% of Patients in KEYNOTE-189 Initial Treatment in Combination with Cisplatin The safety of pemetrexed for injection was evaluated in Study JMDB, a randomized (1:1), open-label, multicenter trial conducted in chemotherapy-naive patients with locally advanced or metastatic NSCLC