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Description

Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys

10.1093/ije/dyv080 6 BowdenJ.Davey SmithG.HaycockP

PMID: 72 MaoH.ZhaoY.LiH.LeiL

DOI: 10.1097/01.CCM.0000025908.95498.A3 28

Here, we have utilized liver-specific overexpression of cation transport regulator homolog 1 ( Chac1 ), a recently identified intracellular GSH-degrading enzyme, to induce hepatic GSH depletion during MASLD progression