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The ATP-depleting futile 5-oxoproline cycle can also contribute to other acute and chronic acetaminophen toxicity syndromes

The physico-chemical stability of the preparation is a subject that deserves attention in this context

RC reports consulting and lecture fees from Astellas, Akern, Baxter, B-Braun, Bristol-Myers Squibb, Boehringer Ingelheim, Eli Lilly, Fresenius Kabi, Lionhealth, Nestl Health Science, Novartis, Nutrisens, MSD, Nutricia, Pfizer, Roche, Servier, Takeda, Viatris, all outside the submitted work

Trans Oncol (2020) 13(8):100785

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The gut microbiota, however, serves as the master regulator of this metabolic network, where microbial BCAAs biosynthesis and catabolism dynamically control systemic BCAAs availability