chac1 glutathione (GSH) depletion by results in a more oxidizing L-2-Hydroxyglutarate sensitizes ferroptosis through ATF3/CHAC1-mediated

L 2 Hydroxyglutarate sensitizes ferroptosis through ATF3 CHAC1 mediated glutathione degradation in hepatocellular carcinoma Cell Death & Disease Transcriptomic analysis of the effect of (E) 3 (3,5 dimethoxyphenyl) 1 (2 methoxyphenyl) prop 2 en 1 one (DPP23) on reactive oxygen species generation in MIA PaCa 2 pancreatic cancer cells Genes & Genomics Springer Nature Link The CHAC1 inhibited Notch3 pathway is involved in temozolomide induced glioma cytotoxicity ScienceDirect Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv Glutathione Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum Stress and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells Functions of glutathione degrading enzymes in tumors. The functions of Download Scientific Diagram

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