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Khuntikeo N, Loilome W, Thinkhamrop B, Chamadol N, Yongvanit P

9 , 3944, doi: 10.1111/crj.12102 (2015)

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Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

The activation of GSH detoxification and metallothionein systems by nucleophilic substances serving as cytoplasmic scavenging agents also accelerates the removal of cisplatin from cells ( 3) The sensitivity of tumour cells to cisplatin is related to the molecular damage caused by the direct binding of cisplatin to its target