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[Google Scholar] 69.Riessland M, Kolisnyk B, Kim TW, Cheng J, Ni J, Pearson JA

It supplies vitamin B12 and Zn: vitamin B12 maintains myelin sheath integrity (preventing prefrontal cortex damage), while zinc modulates TPH1 activityboth deficiencies are associated with higher depression risk (306, 307)

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118,119 For example, ligustrazine delays PVR in HPH by modulating PASMC calcium homeostasis and regulating vasoactive factors (ET-1, NO) 114 while also inhibiting PASMC proliferation by blocking the PI3K/Akt signaling pathway, thereby preventing cell cycle progression from G0/G1 to S phase

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