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(34) reported that APS enhanced autophagy via the PI3K/AKT/mTOR pathway in an in vitro PD cell model, while also inhibiting Bad/Caspase-3 and increasing the Bcl-2/Bax ratio, thus exerting neuroprotective effects

Nevertheless, the alcoholic lungs in ethanol-fed animal models are under increased oxidative stress, have altered nitric oxide metabolism, express abnormal amounts of transforming growth factor TGF-, and are in a chronic proinflammatory state, with up-regulated expressions of IL-1 and tumor necrosis factor TNF-

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Meanwhile, C-PPS/C nanoparticles were found to inhibit the NF-B pathway to reduce the expression of pro-inflammatory genes (Fu X

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