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Down-regulating NQO1 promotes cellular proliferation in K562 cells via elevating DNA synthesis

Vo TTT, Peng TY, Nguyen TH, Bui TNH, Wang CS, Lee WJ et al (2024) The crosstalk between copper-induced oxidative stress and cuproptosis: a novel potential anticancer paradigm

Previous studies established that CAT inhibits ferroptosis by activating transient receptor potential vanilloid type 1 (TRPV1), thereby upregulating GPX4 expression and ameliorating intestinal ischemiareperfusion injury as well as organoid hypoxia-reoxygenation injury (Deng et al., 2021)

Furthermore, placentas of SIRT1-KO mice exhibit senescence markers and morphological disruption [50], which is closely associated with the development of pre-eclampsia